Ex vivo Drug Sensitivity Imaging-based Platform for Primary Acute Lymphoblastic Leukemia Cells

Resistance of acute lymphoblastic leukemia (ALL) cells to chemotherapy, whether present at diagnosis or acquired during treatment, is a major cause of treatment failure. Primary ALL cells are accessible for drug sensitivity testing at the time of new diagnosis or at relapse, but there are major limi...

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Bibliographic Details
Main Authors: Lauren Rowland, Brandon Smart, Anthony Brown, Gino Dettorre, Yoshihiro Gocho, Jeremy Hunt, Wenjian Yang, Satoshi Yoshimura, Noemi Reyes, Guoqing Du, August John, Dylan Maxwell, Wendy Stock, Steven Kornblau, Mary Relling, Hiroto Inaba, Ching Pui, Jean Bourquin, Seth Karol, Charles Mullighan, William Evans, Jun Yang, Kristine Crews
Format: Article
Language:English
Published: Bio-protocol LLC 2023-08-01
Series:Bio-Protocol
Online Access:https://bio-protocol.org/en/bpdetail?id=4731&type=0