Diagnostic challenges of prolonged post-treatment clearance of Plasmodium nucleic acids in a pre-transplant autosplenectomized patient with sickle cell disease

Diagnostic challenges of prolonged post-treatment clearance of Plasmodium nucleic acids in a pre-transplant autosplenectomized patient with sickle cell disease

Abstract Background Autosplenectomy, as a result of sickle cell disease, is an important risk factor for severe malaria. While molecular methods are helpful in providing rapid and accurate infection detection and species identification, the effect of hyposplenism on result interpretation during the...

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Bibliographic Details
Main Authors: Paul M. Luethy, Sean C. Murphy, Annette M. Seilie, Yingda L. Xie, Chuen-Yen Lau, John F. Tisdale, Matthew M. Hsieh, Jessica L. Reinhardt, Anna F. Lau, Gary A. Fahle
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Sickle cell disease
Autosplenectomy
PCR
RT-PCR
18S rRNA
Online Access:http://link.springer.com/article/10.1186/s12936-017-2152-x

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http://link.springer.com/article/10.1186/s12936-017-2152-x

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