Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling

Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling

Macrophages interact with cells in every organ to facilitate tissue development, function and repair. However, the close interaction between macrophages and parenchymal cells can be subverted in disease, particularly cancer. Motility is an essential capacity for macrophages to be able to carry out t...

Full description

Bibliographic Details
Main Authors: Amy R. Dwyer, Eloise L. Greenland, Fiona J. Pixley
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Cancers
Subjects:
macrophage motility
colony-stimulating factor-1
phosphatidyl-inositol-3-kinase
Src family kinases
paracrine interaction
Online Access:http://www.mdpi.com/2072-6694/9/6/68

Internet

http://www.mdpi.com/2072-6694/9/6/68

Similar Items