Elevated Expression of miR-19b Enhances CD8+ T Cell Function by Targeting PTEN in HIV Infected Long Term Non-progressors With Sustained Viral Suppression

Elevated Expression of miR-19b Enhances CD8+ T Cell Function by Targeting PTEN in HIV Infected Long Term Non-progressors With Sustained Viral Suppression

Human immunodeficiency virus (HIV)-infected long-term non-progressors (LTNPs) are of particular importance because of their unique disease progression characteristics. Defined by the maintenance of normal CD4+T cells after more than 8 years of infection, these LTNPs are heterogeneous. Some LTNPs exh...

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Bibliographic Details
Main Authors: Lin-Bo Yin, Cheng-Bo Song, Jie-Fu Zheng, Ya-Jing Fu, Shi Qian, Yong-Jun Jiang, Jun-Jie Xu, Hai-Bo Ding, Hong Shang, Zi-Ning Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
CD8+T cells
long-term non-progressors
microRNA-19b
phosphatase and tensin homolog
HIV
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03140/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.03140/full

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