Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis

Most African trypanosomes, including the veterinary species Trypanosoma brucei brucei and T. congolense are susceptible to lysis by human serum. A recent study by Alsford et al. [PLoS Pathogens (2014) 10, e1004130] has identified a T. b. brucei lysosomal cathepsin with an inhibitory effect on human...

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Bibliographic Details
Main Author: Sam Alsford
Format: Article
Language:English
Published: Shared Science Publishers OG 2014-07-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/increased-trypanosoma-brucei-cathepsin-l-activity-inhibits-human-serum-mediated-trypanolysis/