Notch1 binds and induces degradation of Snail in hepatocellular carcinoma

<p>Abstract</p> <p>Background</p> <p>Hepatocellular carcinoma (HCC) is a common, highly invasive malignant tumor associated with a high mortality rate. We previously reported that the aberrant expression of Snail via activation of reactive oxygen species contributes to...

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Bibliographic Details
Main Authors: Lim Seung-Oe, Kim Hyeon, Quan Xiaoyuan, Ahn Sun-Min, Kim Hongtae, Hsieh David, Seong Je Kyung, Jung Guhung
Format: Article
Language:English
Published: BMC 2011-11-01
Series:BMC Biology
Subjects:
Online Access:http://www.biomedcentral.com/1741-7007/9/83