New maximum likelihood estimators for eukaryotic intron evolution.

The evolution of spliceosomal introns remains poorly understood. Although many approaches have been used to infer intron evolution from the patterns of intron position conservation, the results to date have been contradictory. In this paper, we address the problem using a novel maximum likelihood me...

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Bibliographic Details
Main Authors: Hung D Nguyen, Maki Yoshihama, Naoya Kenmochi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1323467?pdf=render