Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia

<p>Abstract</p> <p>Background</p> <p>Stroke is one of the leading causes of death worldwide and a major cause of morbidity and mortality in the United States of America. Brain ischemia-reperfusion (IR) triggers a complex series of biochemical events including inflammati...

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Bibliographic Details
Main Authors: Singh Inderjit, Singh Avtar K, Elango Chinnasamy, Ansari Mubeen A, Giri Shailendra, Jatana Manu, Khan Mushfiquddin
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/3/1/12