Topical Protease Inhibitor Decreases Anal Carcinogenesis in a Transgenic Mouse Model of HPV Anal Disease

Topical Protease Inhibitor Decreases Anal Carcinogenesis in a Transgenic Mouse Model of HPV Anal Disease

Anal cancer is a major health problem. This study seeks to determine if the topical protease inhibitor Saquinavir (SQV), is effective at the prevention of anal cancer in transgenic mice with established anal dysplasia. <i>K14E6/E7</i> mice were entered into the study when the majority sp...

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Bibliographic Details
Main Authors: Laura C. Gunder, Hillary R. Johnson, Evan Yao, Tyra H. Moyer, Heather A. Green, Nathan Sherer, Wei Zhang, Evie H. Carchman
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Viruses
Subjects:
anal dysplasia
anal cancer
squamous cell carcinoma of the anus
HPV
chemoprevention
Online Access:https://www.mdpi.com/1999-4915/15/4/1013

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https://www.mdpi.com/1999-4915/15/4/1013

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