3-Bromo-4,5-Dihydroxybenzaldehyde Protects Against Myocardial Ischemia and Reperfusion Injury Through the Akt-PGC1α-Sirt3 Pathway

3-Bromo-4,5-Dihydroxybenzaldehyde Protects Against Myocardial Ischemia and Reperfusion Injury Through the Akt-PGC1α-Sirt3 Pathway

Natural marine products are useful candidates for the treatment of oxidative and inflammatory diseases, including myocardial ischemia. 3-bromo-4,5 - dihydroxybenzaldehyde (BDB), a natural bromophenol isolated from marine red algae, has been shown to display anti-microbial, anti-oxidative, anti-cance...

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Bibliographic Details
Main Authors: Shu-Guang Qin, Hong-Yan Tian, Jin Wei, Zhen-Hua Han, Ming-Juan Zhang, Guang-Hua Hao, Xin Liu, Long-Fei Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
3-bromo-4
5-dihydroxybenzaldehyde
cardiomyocytes
ischemia
oxidative stress
Sirt3
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00722/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00722/full

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