Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients

Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients

Abstract Purpose To explore the role and effects of the single-nucleotide polymorphisms (SNPs) of the two functionally related indoleamine 2,3-dioxygenase (IDO) isoforms on IDO activity in the Chinese Han ethnic population. Methods A total of 151 consecutive patients of Chinese Han ethnicity (99 men...

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Bibliographic Details
Main Authors: Tingming Cao, Guangming Dai, Hongqian Chu, Chengcheng Kong, Huijuan Duan, Na Tian, Zhaogang Sun
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Hereditas
Subjects:
Indoleamine 2,3-dioxygenase
Tryptophan
Kynurenine
Single-nucleotide polymorphism
Online Access:https://doi.org/10.1186/s41065-022-00219-y

Internet

https://doi.org/10.1186/s41065-022-00219-y

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