Tetrahydrocurcumin Upregulates the Adiponectin-AdipoR Pathway and Improves Insulin Signaling and Pancreatic β-Cell Function in High-Fat Diet/Streptozotocin-Induced Diabetic Obese Mice

Impairment of adiponectin production and function is closely associated with insulin resistance and type 2 diabetes, which are linked to obesity. Studies in animal models have documented the anti-diabetic effects of tetrahydrocurcumin (THC). Although several possible mechanisms have been proposed, t...

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Bibliographic Details
Main Authors: Yi-Zhen Tsai, Mei-Ling Tsai, Li-Yin Hsu, Chi-Tang Ho, Ching-Shu Lai
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/12/4552