A tyrosine residue on the TSH receptor stabilizes multimer formation.

The thyrotropin stimulating hormone receptor (TSHR) is a G protein coupled receptor (GPCR) with a large ectodomain. The ligand, TSH, acting via this receptor regulates thyroid growth and thyroid hormone production and secretion. The TSH receptor (TSHR) undergoes complex post-translational modificati...

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Bibliographic Details
Main Authors: Rauf Latif, Krzysztof Michalek, Syed Ahmed Morshed, Terry F Davies
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2829087?pdf=render