Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

Relaxin-3 is a highly conserved neuropeptide in vertebrate species and binds to the Class A G protein-coupled receptor RXFP3. Relaxin-3 is involved in a wide range of behaviours, including feeding, stress responses, arousal and cognitive processes and therefore targeting of RXFP3 may be relevant for...

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Bibliographic Details
Main Authors: Ross eBathgate, Maria eOh, Jason eLing, Quentin eKaas, Akhter eHossain, Paul eGooley, Johan eRosengren
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Endocrinology
Subjects:
modelling
peptide
GPCR
relaxin-3
RXFP3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00013/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00013/full

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