Modeling of High-Density Compaction of Pharmaceutical Tablets Using Multi-Contact Discrete Element Method

The purpose of this work is to simulate the powder compaction of pharmaceutical materials at the microscopic scale in order to better understand the interplay of mechanical forces between particles, and to predict their compression profiles by controlling the microstructure. For this task, the new f...

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Bibliographic Details
Main Authors: Kostas Giannis, Carsten Schilde, Jan Henrik Finke, Arno Kwade
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/13/12/2194