The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

The cytoskeleton adaptor protein Sorbs1 controls the development of lymphatic and venous vessels in zebrafish

Abstract Background Lymphangiogenesis, the formation of lymphatic vessels, is tightly linked to the development of the venous vasculature, both at the cellular and molecular levels. Here, we identify a novel role for Sorbs1, the founding member of the SoHo family of cytoskeleton adaptor proteins, in...

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Bibliographic Details
Main Authors: Alexandra Veloso, Anouk Bleuart, Louise Conrard, Tanguy Orban, Jonathan Bruyr, Pauline Cabochette, Raoul F. V. Germano, Giel Schevenels, Alice Bernard, Egor Zindy, Sofie Demeyer, Benoit Vanhollebeke, Franck Dequiedt, Maud Martin
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Biology
Subjects:
Sorbs1
Lymphangiogenesis
BMP signaling
Vegfc
Angiogenesis
Rho GTPases
Online Access:https://doi.org/10.1186/s12915-024-01850-z

Internet

https://doi.org/10.1186/s12915-024-01850-z

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