Untargeted Fecal Metabolomic Analyses across an Industrialization Gradient Reveal Shared Metabolites and Impact of Industrialization on Fecal Microbiome-Metabolome Interactions

Untargeted Fecal Metabolomic Analyses across an Industrialization Gradient Reveal Shared Metabolites and Impact of Industrialization on Fecal Microbiome-Metabolome Interactions

ABSTRACT The metabolome is a central determinant of human phenotypes and includes the plethora of small molecules produced by host and microbiome or taken up from exogenous sources. However, studies of the metabolome have so far focused predominantly on urban, industrialized populations. Through an...

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Bibliographic Details
Main Authors: Jacob J. Haffner, Mitchelle Katemauswa, Thérèse S. Kagone, Ekram Hossain, David Jacobson, Karina Flores, Adwaita R. Parab, Alexandra J. Obregon-Tito, Raul Y. Tito, Luis Marin Reyes, Luzmila Troncoso-Corzo, Emilio Guija-Poma, Nicolas Meda, Hélène Carabin, Tanvi P. Honap, Krithivasan Sankaranarayanan, Cecil M. Lewis, Laura-Isobel McCall
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mSystems
Subjects:
human microbiome
industrialization
mass spectrometry
metabolomics
Online Access:https://journals.asm.org/doi/10.1128/msystems.00710-22

Internet

https://journals.asm.org/doi/10.1128/msystems.00710-22

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