c-Myc Drives inflammation of the maternal-fetal interface, and neonatal lung remodeling induced by intra-amniotic inflammation

Background: Intra-amniotic inflammation (IAI) is associated with increased risk of preterm birth and bronchopulmonary dysplasia (BPD), but the mechanisms by which IAI leads to preterm birth and BPD are poorly understood, and there are no effective therapies for preterm birth and BPD. The transcripti...

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Main Authors: April W. Tan, Xiaoying Tong, Silvia Alvarez-Cubela, Pingping Chen, Aline Guimarães Santana, Alejo A. Morales, Runxia Tian, Rae Infante, Vanessa Nunes de Paiva, Shathiyah Kulandavelu, Merline Benny, Juan Dominguez-Bendala, Shu Wu, Karen C. Young, Claudia O. Rodrigues, Augusto F. Schmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1245747/full