Medium-chain fatty acids modify macrophage expression of metabolic and inflammatory genes in a PPAR β/δ-dependent manner

Abstract There is great interest on medium chain fatty acids (MCFA) for cardiovascular health. We explored the effects of MCFA on the expression of lipid metabolism and inflammatory genes in macrophages, and the extent to which they were mediated by the nuclear receptor peroxisome proliferator-activ...

Full description

Bibliographic Details
Main Authors: Paula V. Gaete, Luz D. Nieves-Barreto, Valentina Guatibonza-García, Mónica Losada-Barragán, Karina Vargas-Sánchez, Carlos O. Mendivil
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38700-x