Advances in genetic profile and therapeutic strategy of pulmonary large cell neuroendocrine carcinoma

Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine carcinoma (HGNEC) accounting for 3% of primary lung cancer, and characterized by strong invasion, high heterogeneity, and extremely poor prognosis. At present, the diagnosis and treatment of LCNEC remains controvers...

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Bibliographic Details
Main Authors: Siyu Zhu, Xinyue Wang, Hui Li, Peiyan Zhao, Jingjing Liu, Liang Zhang, Ying Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1326426/full