Differential vulnerability of the dentate gyrus to tauopathies in dementias

Differential vulnerability of the dentate gyrus to tauopathies in dementias

Abstract The dentate gyrus (DG), a key hippocampal subregion in memory processing, generally resists phosphorylated tau accumulation in the amnestic dementia of the Alzheimer’s type due to Alzheimer’s disease (DAT-AD), but less is known about the susceptibility of the DG to other tauopathies. Here,...

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Bibliographic Details
Main Authors: Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E. Flanagan, Rudolph Castellani, Eileen H. Bigio, M. Marsel Mesulam, Changiz Geula, Tamar Gefen
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Acta Neuropathologica Communications
Subjects:
Dentate gyrus
Frontotemporal lobar degeneration
Tauopathy
Primary progressive aphasia
Online Access:https://doi.org/10.1186/s40478-022-01485-7

Internet

https://doi.org/10.1186/s40478-022-01485-7

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