Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

Abstract Background Direct cardiac reprogramming is currently being investigated for the generation of cells with a true cardiomyocyte (CM) phenotype. Based on the original approach of cardiac transcription factor-induced reprogramming of fibroblasts into CM-like cells, various modifications of that...

Full description

Bibliographic Details
Main Authors: Dipthi Bachamanda Somesh, Kristin Klose, Janita A. Maring, Désirée Kunkel, Karsten Jürchott, Stephanie I. Protze, Oliver Klein, Grit Nebrich, Matthias Becker, Ulrike Krüger, Timo Z. Nazari-Shafti, Volkmar Falk, Andreas Kurtz, Manfred Gossen, Christof Stamm
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Stem Cell Research & Therapy
Subjects:
Cell therapy
Direct reprogramming
Fibroblast
Induced cardiomyocyte precursor
Molecular beacon
Myocardial infarction
Online Access:https://doi.org/10.1186/s13287-023-03519-w

Internet

https://doi.org/10.1186/s13287-023-03519-w

Similar Items