PU.1 controls the expression of long noncoding RNA HOTAIRM1 during granulocytic differentiation

PU.1 controls the expression of long noncoding RNA HOTAIRM1 during granulocytic differentiation

Abstract Background Long noncoding RNA HOX antisense intergenic RNA myeloid 1 (HOTAIRM1) has been characterized as a critical factor in all-trans retinoic acid (ATRA)-induced differentiation of acute promyelocytic leukemia (APL) cells. However, the essential transcription factor for gene expression...

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Bibliographic Details
Main Authors: Shuyong Wei, Ming Zhao, Xiaoling Wang, Yizhen Li, Kankan Wang
Format: Article
Language:English
Published: BMC 2016-05-01
Series:Journal of Hematology & Oncology
Subjects:
HOTAIRM1
PU.1
APL
PML-RARα
Transcriptional regulation
Online Access:http://link.springer.com/article/10.1186/s13045-016-0274-1

Internet

http://link.springer.com/article/10.1186/s13045-016-0274-1

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