EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers

EZH2, HIF-1, and Their Inhibitors: An Overview on Pediatric Cancers

During the past decades, several discoveries have established the role of epigenetic modifications and cellular microenvironment in tumor growth and progression. One of the main representatives concerning epigenetic modification is the polycomb group (PcG). It is composed of different highly conserv...

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Bibliographic Details
Main Authors: Marco Papale, Elisabetta Ferretti, Giuseppe Battaglia, Diana Bellavia, Antonello Mai, Marco Tafani
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pediatrics
Subjects:
HIF-1
EZH2
tumors
cancers
oncology
hypoxia
Online Access:https://www.frontiersin.org/article/10.3389/fped.2018.00328/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2018.00328/full

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