Therapy-induced normal tissue damage promotes breast cancer metastasis

Therapy-induced normal tissue damage promotes breast cancer metastasis

Summary: Disseminated tumor cells frequently exhibit a period of dormancy, rendering them chemotherapy insensitive; conversely, the systemic delivery of chemotherapies can result in normal tissue damage. Using multiple mouse and human breast cancer models, we demonstrate that prior chemotherapy admi...

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Bibliographic Details
Main Authors: Douglas W. Perkins, Ivana Steiner, Syed Haider, David Robertson, Richard Buus, Lynda O'Leary, Clare M. Isacke
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Cellular therapy
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223025804

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223025804

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