Dynamic DNA methylation landscape defines brown and white cell specificity during adipogenesis

Objective: DNA methylation may be a stable epigenetic contributor to defining fat cell lineage. Methods: We performed reduced representation bisulfite sequencing (RRBS) and RNA-seq to depict a genome-wide integrative view of the DNA methylome and transcriptome during brown and white adipogenesis. Re...

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Bibliographic Details
Main Authors: Yen Ching Lim, Sook Yoong Chia, Shengnan Jin, Weiping Han, Chunming Ding, Lei Sun
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S221287781630120X