5-HMF attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis mice by inhibiting the MIF-CD74 interaction

The neuroprotective role of 5-hydroxymethyl-2-furfural (5-HMF) has been demonstrated in a variety of neurological diseases. The aim of this study is to investigate the effect of 5-HMF on multiple sclerosis (MS). IFN-γ-stimulated murine microglia (BV2 cells) are considered a cell model of MS. With 5-...

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Những tác giả chính: Guan Dongsheng, Li Yingxia, Cui Yinglin, Zhao Huanghong, Dong Ning, Wang Kun, Ren Deqi, Song Tiantian, Wang Xiaojing, Jin Shijie, Gao Yinghe, Wang Mengmeng
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: China Science Publishing & Media Ltd. 2023-07-01
Loạt:Acta Biochimica et Biophysica Sinica
Những chủ đề:
Truy cập trực tuyến:https://www.sciengine.com/doi/10.3724/abbs.2023105