A Computational Approach Applied to the Study of Potential Allosteric Inhibitors Protease NS2B/NS3 from Dengue Virus

A Computational Approach Applied to the Study of Potential Allosteric Inhibitors Protease NS2B/NS3 from Dengue Virus

Dengue virus (DENV) is a danger to more than 400 million people in the world, and there is no specific treatment. Thus, there is an urgent need to develop an effective method to combat this pathology. NS2B/NS3 protease is an important biological target due it being necessary for viral replication an...

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Bibliographic Details
Main Authors: Renato A. da Costa, João A. P. da Rocha, Alan S. Pinheiro, Andréia do S. S. da Costa, Elaine C. M. da Rocha, Rai. C. Silva, Arlan da S. Gonçalves, Cleydson B. R. Santos, Davi do S. B. Brasil
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
Dengue
NS2B/NS3pro
allosteric site
molecular docking
molecular dynamics and free energy
Online Access:https://www.mdpi.com/1420-3049/27/13/4118

Internet

https://www.mdpi.com/1420-3049/27/13/4118

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