Quercetin as a Potential Modulator of P-Glycoprotein Expression and Function in Cells of Human Pancreatic Carcinoma Line Resistant to Daunorubicin

P-glycoprotein (P-gp) is one of the ABC transporters responsible for the resistance of several tumours to successful chemotherapy. Numerous agents are capable of interfering with the P-gp-mediated export of drugs but unfortunately most of them produce serious side effects. Some plant polyphenols, in...

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Bibliographic Details
Main Authors: Piotr Dziegiel, Magdalena Chmielewska, Maciej Zabel, Sylwia Borska, Miroslaw Sopel
Format: Article
Language:English
Published: MDPI AG 2010-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/2/857/