Correlation between the genotoxicity endpoints measured by two different genotoxicity assays: comet assay and CBMN assay

The cytokinesis-block micronucleus cytome (CBMN) assay is a comprehensive system for measuring DNA damage; cytostasis and cytotoxicity-DNA damage events are scored specifically in once-divided binucleated cells. The endpoints possible to be measured are micronuclei (MN), a biomarker of chromosome br...

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Bibliographic Details
Main Authors: Carina Ladeira, Susana Viegas, Manuel C. Gomes
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/conf.fgene.2015.01.00027/full