mRNA vaccine encoding Gn provides protection against severe fever with thrombocytopenia syndrome virus in mice

Abstract We developed a promising mRNA vaccine against severe fever with thrombocytopenia syndrome (SFTS), an infectious disease caused by the SFTS virus that is primarily transmitted through tick bites. Administration of lipid nanoparticle-encapsulated mRNA-Gn successfully induced neutralizing anti...

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Bibliographic Details
Main Authors: Jae-Yong Kim, Kyeongseok Jeon, Sang-In Park, Yoo-Jin Bang, Hyeong-Jun Park, Hye Won Kwak, Do-Hyung Kim, Soo-Yeon Lee, Eun-Jin Choi, Nam-Hyuk Cho, Jae-Hwan Nam
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00771-2