mRNA vaccine encoding Gn provides protection against severe fever with thrombocytopenia syndrome virus in mice
Abstract We developed a promising mRNA vaccine against severe fever with thrombocytopenia syndrome (SFTS), an infectious disease caused by the SFTS virus that is primarily transmitted through tick bites. Administration of lipid nanoparticle-encapsulated mRNA-Gn successfully induced neutralizing anti...
Main Authors: | Jae-Yong Kim, Kyeongseok Jeon, Sang-In Park, Yoo-Jin Bang, Hyeong-Jun Park, Hye Won Kwak, Do-Hyung Kim, Soo-Yeon Lee, Eun-Jin Choi, Nam-Hyuk Cho, Jae-Hwan Nam |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-023-00771-2 |
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