Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor

Summary: A mesenchymal cell activation is a hallmark event of pulmonary fibrosis. Alveolar type 2 (AT2) cells are progenitor cells that maintain alveolar homeostasis, and their damage is assumed to be an initiating event for pulmonary fibrosis. However, the interaction between the lung fibrogenic mi...

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Bibliographic Details
Main Authors: Ryo Miyata, Koichi Hasegawa, Toshi Menju, Akihiko Yoshizawa, Akira Watanabe, Toyohiro Hirai, Hiroshi Date, Atsuyasu Sato
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222011841