L‐type Voltage‐Gated calcium channels partly mediate Mechanotransduction in the intervertebral disc

Abstract Background Intervertebral disc (IVD) degeneration continues to be a major global health challenge, with strong links to lower back pain, while the pathogenesis of this disease is poorly understood. In cartilage, much more is known about mechanotransduction pathways involving the strain‐gene...

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Bibliographic Details
Main Authors: Philip Poillot, Joseph W. Snuggs, Christine L. Le Maitre, Jacques M. Huyghe
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:JOR Spine
Subjects:
Online Access:https://doi.org/10.1002/jsp2.1213