An engineered ligand-responsive Csy4 endoribonuclease controls transgene expression from Sendai virus vectors

An engineered ligand-responsive Csy4 endoribonuclease controls transgene expression from Sendai virus vectors

Abstract Background Viral vectors are attractive gene delivery vehicles because of their broad tropism, high transduction efficiency, and durable expression. With no risk of integration into the host genome, the vectors developed from RNA viruses such as Sendai virus (SeV) are especially promising....

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Bibliographic Details
Main Authors: Takumi Kishimoto, Ken Nishimura, Kana Morishita, Aya Fukuda, Yusaku Miyamae, Yutaro Kumagai, Kimio Sumaru, Mahito Nakanishi, Koji Hisatake, Masayuki Sano
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Biological Engineering
Subjects:
Sendai virus
Csy4
Ligand
Gene regulation
ES cells
Neural differentiation
Online Access:https://doi.org/10.1186/s13036-024-00404-9

Internet

https://doi.org/10.1186/s13036-024-00404-9

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