Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

Abstract Background The viral G-protein-coupled receptor (vGPCR) BILF1 encoded by the Epstein–Barr virus (EBV) is an oncogene and immunoevasin and can downregulate MHC-I molecules at the surface of infected cells. MHC-I downregulation, which presumably occurs through co-internalization with EBV-BILF...

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Bibliographic Details
Main Authors: Maša Mavri, Sanja Glišić, Milan Senćanski, Milka Vrecl, Mette M. Rosenkilde, Katja Spiess, Valentina Kubale
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cellular & Molecular Biology Letters
Subjects:
vGPCR
BILF1
Endocytosis
Internalization
Dynamin
Caveolin
Online Access:https://doi.org/10.1186/s11658-023-00427-y

Internet

https://doi.org/10.1186/s11658-023-00427-y

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