Membrane Drug Transporters and Chemoresistance in Human Pancreatic Carcinoma
Pancreatic cancer ranks among the tumors most resistant to chemotherapy. Such chemoresistance of tumors can be mediated by various cellular mechanisms including dysregulated apoptosis or ineffective drug concentration at the intracellular target sites. In this review, we highlight recent advances in...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-12-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/3/1/106/ |