Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner

Osthole Antagonizes Microglial Activation in an NRF2-Dependent Manner

Microglia are neuroglia in the brain with an innate immune function and participate in the progress of neurodegenerative diseases. Osthole (OST) is a coumarin derivative extracted from <i>Cnidium monnieri</i> and bears a microglia-antagonizing ability. However, the underlying mechanism o...

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Bibliographic Details
Main Authors: Chuan-Hsiu Liu, Mei-Ying Chen, Yueh-Hsiung Kuo, Jack Cheng, Li-Zhong Chang, Meng-Shiun Chang, Tsai-Ni Chuang, Wen-Tsong Hsieh, Yan-Ru Xiao, Bor-Tsang Wu, Wei-Yong Lin, Hsin-Ping Liu
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
osthole
NRF2
microglia
Online Access:https://www.mdpi.com/1420-3049/28/2/507

Internet

https://www.mdpi.com/1420-3049/28/2/507

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