CRISPR screening in hematology research: from bulk to single-cell level

Abstract The CRISPR genome editing technology has revolutionized the way gene function is studied. Genome editing can be achieved in single genes or for thousands of genes simultaneously in sensitive genetic screens. While conventional genetic screens are limited to bulk measurements of cell behavio...

Full description

Bibliographic Details
Main Authors: Sarah Meyers, Sofie Demeyer, Jan Cools
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-023-01495-5