CRISPR screening in hematology research: from bulk to single-cell level

Abstract The CRISPR genome editing technology has revolutionized the way gene function is studied. Genome editing can be achieved in single genes or for thousands of genes simultaneously in sensitive genetic screens. While conventional genetic screens are limited to bulk measurements of cell behavio...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Sarah Meyers, Sofie Demeyer, Jan Cools
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: BMC 2023-10-01
Cyfres:Journal of Hematology & Oncology
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s13045-023-01495-5