Enantioselective total synthesis of (R)-(−)-complanine

A route is described for the enantioselective synthesis of (R)-(−)-complanine, a marine natural product isolated from Eurythoe complanata, and known to be a causative agent in inflammation. An organocatalytic, asymmetric oxyamination of a homoconjugated all-Z-dienal intermediate provides versatile a...

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Bibliographic Details
Main Authors: Krystal A. D. Kamanos, Jonathan M. Withey
Format: Article
Language:English
Published: Beilstein-Institut 2012-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.8.192