Hepatitis B Virus-Encoded HBsAg Contributes to Hepatocarcinogenesis by Inducing the Oncogenic Long Noncoding RNA LINC00665 through the NF-κB Pathway

Hepatitis B Virus-Encoded HBsAg Contributes to Hepatocarcinogenesis by Inducing the Oncogenic Long Noncoding RNA LINC00665 through the NF-κB Pathway

ABSTRACT Clinical and in vivo studies have demonstrated a role for hepatitis B virus (HBV)-encoded HBsAg (hepatitis B surface antigen) in HBV-related hepatocellular carcinoma (HCC); however, the underlying mechanisms remain largely unknown. Here, we investigated the role of HBsAg in regulating long...

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Bibliographic Details
Main Authors: Shivaksh Ahluwalia, Belal Ahmad, Uzma Salim, Dipannita Ghosh, Vinay Kamuju, Arpita Ghosh, Khadija Dabeer, Manoj B. Menon, Perumal Vivekanandan
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
HBsAg
LINC00665
NF-κB
hepatitis B virus
hepatocellular carcinoma
long noncoding RNA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02731-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.02731-21

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