Chromatin regulators, phenotypic robustness and autism risk

Though extensively characterized clinically, the causes of autism spectrum disorder (ASD) remain a mystery. ASD is known to have a strong genetic basis, but it is genetically very heterogeneous. Recent studies have estimated that de novo disruptive mutations in hundreds of genes may contribute to AS...

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Bibliographic Details
Main Authors: Reut eSuliman, Eyal eBen-David, Sagiv eShifman
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00081/full