Repeated inflammatory dural stimulation-induced cephalic allodynia causes alteration of gut microbial composition in rats

Repeated inflammatory dural stimulation-induced cephalic allodynia causes alteration of gut microbial composition in rats

Abstract Background Gut microbial dysbiosis and gut-brain axis dysfunction have been implicated in the pathophysiology of migraine. However, it is unclear whether migraine-related cephalic allodynia could induce the alteration of gut microbial composition. Methods A classic migraine rat model was es...

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Bibliographic Details
Main Authors: Shuai Miao, Wenjing Tang, Heng Li, Bozhi Li, Chunxiao Yang, Wei Xie, Tao Wang, Wenhao Bai, Zihua Gong, Zhao Dong, Shengyuan Yu
Format: Article
Language:English
Published: BMC 2022-06-01
Series:The Journal of Headache and Pain
Subjects:
Migraine
Cephalic allodynia
Gut microbiota
16 S rRNA gene sequencing
Gut-brain axis
Online Access:https://doi.org/10.1186/s10194-022-01441-9

Internet

https://doi.org/10.1186/s10194-022-01441-9

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