A novel coumarin derivative DBH2 inhibits proliferation and induces apoptosis of chronic myeloid leukemia cells

A novel coumarin derivative DBH2 inhibits proliferation and induces apoptosis of chronic myeloid leukemia cells

With the development of tyrosine kinase inhibitor (TKI) resistance, finding the novel effective chemotherapeutic agent is of seminal importance for chronic myelogenous leukemia (CML) treatment. This study aims to find the effective anti-leukemic candidates and investigate the possible underlying mec...

Full description

Bibliographic Details
Main Authors: Jiajia Xin, Huijie Zhang, Dandan Yin, Ning An, Yaozhen Chen, Jinmei Xu, Jing Zhang, Zhixin Liu, Yongsheng Liu, Wen Yin, Mingkai Li, Xingbin Hu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-03-01
Series:Genes and Diseases
Subjects:
Apoptosis
Caspase
Chronic myeloid leukemia
Coumarin
STAT
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222002422

Internet

http://www.sciencedirect.com/science/article/pii/S2352304222002422

Similar Items