Identification of novel AKT1 inhibitors from Sapria himalayana bioactive compounds using structure-based virtual screening and molecular dynamics simulations

Identification of novel AKT1 inhibitors from Sapria himalayana bioactive compounds using structure-based virtual screening and molecular dynamics simulations

Abstract Through the experimental and computational analyses, the present study sought to elucidate the chemical composition and anticancer potential of Sapria himalayana plant extract (SHPE). An in vitro analysis of the plant extract was carried out to determine the anticancer potential. Further, n...

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Bibliographic Details
Main Authors: Laldinfeli Ralte, Hmingremhlua Sailo, Rakesh Kumar, Laldinliana Khiangte, Nachimuthu Senthil Kumar, Yengkhom Tunginba Singh
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Sapria himalayana
Cytotoxicity
Network pharmacology
Molecular docking
Molecular dynamic simulation
Online Access:https://doi.org/10.1186/s12906-024-04415-3

Internet

https://doi.org/10.1186/s12906-024-04415-3

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