Structure-based in silico investigation of antagonists of human ribonucleotide reductase from Annona muricata

Structure-based in silico investigation of antagonists of human ribonucleotide reductase from Annona muricata

Human ribonucleotide reductase (HRR) also known as ribonuceotide diphosphate reductase catalyzes the conversion of ribonucleotide to deoxyribonuceotides which is the rate limiting step in the synthesis of DNA, establishing the enzyme as a vital therapeutic target in discovery of cancer drugs. Hence,...

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Bibliographic Details
Main Authors: Damilola A. Omoboyowa, Damilola S. Bodun, Jamiyu A. Saliu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Ribonucleotide reductase
In silico
Cancer
Schrodinger
Inhibitors
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914823000679

Internet

http://www.sciencedirect.com/science/article/pii/S2352914823000679

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