Structure-based in silico investigation of antagonists of human ribonucleotide reductase from Annona muricata

Structure-based in silico investigation of antagonists of human ribonucleotide reductase from Annona muricata

Human ribonucleotide reductase (HRR) also known as ribonuceotide diphosphate reductase catalyzes the conversion of ribonucleotide to deoxyribonuceotides which is the rate limiting step in the synthesis of DNA, establishing the enzyme as a vital therapeutic target in discovery of cancer drugs. Hence,...

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Detalles Bibliográficos
Autores principales: Damilola A. Omoboyowa, Damilola S. Bodun, Jamiyu A. Saliu
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2023-01-01
Colección:Informatics in Medicine Unlocked
Materias:
Ribonucleotide reductase
In silico
Cancer
Schrodinger
Inhibitors
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2352914823000679

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