Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

Conformational change of the Bordetella response regulator BvgA accompanies its activation of the B. pertussis virulence gene fhaB

The BvgAS two-component system regulates virulence gene expression in Bordetella pertussis. Although precise three-dimensional structural information is not available for the response regulator BvgA, its sequence conservation with E. coli NarL and previous studies have indicated that it is composed...

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Bibliographic Details
Main Authors: David Kim, John Tracey, Manuel Becerra Flores, Kanita Chaudhry, Rafae Nasim, Abraham Correa-Medina, Leslie Knipling, Qing Chen, Scott Stibitz, Lisa M.M. Jenkins, Kyung Moon, Tim Cardozo, Deborah M. Hinton
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Bordetella pertussis
Response regulator
BvgA
Two-component system
FeBABE
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022004895

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http://www.sciencedirect.com/science/article/pii/S2001037022004895

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