Investigation of Direct and Retro Chromone-2-Carboxamides Based Analogs of <i>Pseudomonas aeruginosa</i> Quorum Sensing Signal as New Anti-Biofilm Agents

Investigation of Direct and Retro Chromone-2-Carboxamides Based Analogs of <i>Pseudomonas aeruginosa</i> Quorum Sensing Signal as New Anti-Biofilm Agents

Biofilm formation is considered a major cause of therapeutic failure because bacteria in biofilms have higher protection against antimicrobials. Thus, biofilm-related infections are extremely challenging to treat and pose major concerns for public health, along with huge economic impacts. <i>P...

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Bibliographic Details
Main Authors: Jeanne Trognon, Gonzalo Vera, Maya Rima, Jean-Luc Stigliani, Laurent Amielet, Salomé El Hage, Barbora Lajoie, Christine Roques, Fatima El Garah
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceuticals
Subjects:
<i>Pseudomonas aeruginosa</i>
Quorum Sensing inhibition
chromone carboxamides
PqsR
<i>Pseudomonas</i> Quinolone Signal (PQS)
biofilms
Online Access:https://www.mdpi.com/1424-8247/15/4/417

Internet

https://www.mdpi.com/1424-8247/15/4/417

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